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Level of Nutritional Status, Ferritin and Albumin Serum in Adult Pulmonary Tuberculosis Intensive Phase Patient
Last modified: 2019-10-08
Abstract
Mycobacterium tuberculosis induce tissue damage and inflammation, increase C-Reactive Protein (CRP) production, which also will induce ferritin production through inflammatory pathway. Iron status, especially ferritin serum, could help in assesing treatment failure, TB recurrency, and TB motality. TB infection causing protein-energi malnutrition and albumin level decline. The purpose of this study is to find out the relation between ferritin, albumin and BMI with anemia in intensive phase adult pulmonary tuberculosis. This is an observational analytic studies. The study was done in Sentra Medika Hospital, Depok. 25 sample subject were chosen by consecutive sampling methode. Independent variable in this study were serum ferritin level, albumin level, and Body Mass Index (BMI), while the dependent variable was the degree of anemia (stated by Hemoglobin level). Each subject were measured for body height, body weight, and haematological examination. Data result the analyzed using Chi-square test. This study shows 11 subject experience moderate anemia (44%), 7 subject experience mild anemia (28%), ferritin level increase in 19 subject (76%), normal albumin level in 22 subject (88%), underweight in 11 subject (44%), normoweight in 10 subject (40%). Relation between ferritin level and anemia statistically not significant (p=1), also between albumin level and anemia statistically not significant (p=0.283). Only BMI and anemia statistically significant (p=0.02). Ferritin and albumin level both have no relation with anemia, only BMI has. Anemia along with high ferritin level leading to anemia in chronic disease.
Keywords
albumin serum, anemia, body mass index, ferritin serum